COVID Antibody Test

COVID Antibody Test

The COVID-19 antibody tests provide qualitative detection of IgM and IgG antibodies against SARS- CoV-2 in individuals suspected of COVID-19. After infection with COVID-19 the virus antigen stimulates the immune system to produce antibodies that can be detected in the blood.

Among these antibodies, IgM antibodies appear early and are mostly positive after 3-5 days of infection. After 7 days IgG antibodies increase four times or more than that of IgM.



Quick Facts:
  • Purpose: Past exposure
  • Method: Blood Draw
  • Result in: 3-5 days
  • Test: Beckman Coulter, Roche
  • Cost: Covered by most insurances
  • FDA Emergency Use Authorization


  • Through LabFinder you can schedule Rapid PCR COVID Nasal Swab and Rapid Antigen COVID Test as well as the COVID PCR Swab Testing.
  • Both the Rapid COVID Test and COVID PCR Swab Test can determine if someone is currently infected with COVID-19, the COVID Antibody Test is used to determine if someone has had COVID-19 in the past.
  • All three tests are important and have their specific uses. Please note, all labs have instituted all procedural changes recommended by the CDC to ensure that all of our patients’ safety is protected in every way possible when they come to the office or test facility for appointments while the pandemic is ongoing.


COVID Antibody Test

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When to test

COVID Antibody Test is recommended to be used on patients with at least 3 days after onset of symptoms or 7-10 days after infection with the virus 2-4.

    Symptoms include fever or chills, cough, shortness of breath or difficulty breathing, fatigue, muscle or body aches, headache, new loss of taste or smell, sore throat, congestion or runny nose, nausea or vomiting, and diarrhea.

What Is SARS-CoV-2 and What Is COVID-19?

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the official name of the novel coronavirus that is currently causing a worldwide pandemic. COVID-19 is the official name of the respiratory disease caused by SARS-CoV-2. SARS-CoV-2 is highly contagious and is transmitted through respiratory droplets and contact with contaminated surfaces.

What Is The Incubation Period For COVID-19?

Although several studies are still in progress, according to the March 10th, 2020 study published in the Annals of Internal Medicine, the incubation period for COVID-19 as measured from publicly confirmed cases is as follows: median incubation period is 5 days.  

What is the COVID Antibody Test?

The COVID Antibody Test test is a blood test that provides qualitative and quantitative detection of IgM and IgG antibodies against the SARS-CoV-2 in individuals suspected of COVID-19. After infection, the virus antigen stimulates the immune system to produce antibodies that can be detected in the blood. Among these antibodies, the IgM antibodies appear early and are mostly positive after 3-5 days of onset. The IgM titers then decrease while the IgG antibody potency starts to rise rapidly. During the recovery phase, the titer of the IgG antibody may increase four times or more compared to the acute phase.  

Why the COVID Antibody Test?

Combined with the Nasal Swab by RT-qPCR, the COVID-19 Serological Antibody Blood Test offers a valuable diagnostic tool in identifying infected patients. According to recent studies, the COVID-19 antibodies are not detectable before 3 days after onset of symptoms (or at least 7 to 10 days after infection). However, antibody tests can detect past infection because virus-specific antibodies can persist in the blood for several weeks/months after the onset of symptoms. Since the exact time of infection is often unknown, combining RT-qPCR (nasal swab) and IgM/IgG testing (blood test) can improve the accuracy of the COVID-19 diagnosis.  

Who Can Be Tested?

COVID Antibody Test is recommended to be used on patients with at least 5 days after onset of symptoms or 7-10 days after infection with the virus.  

What Are The Guidelines On Testing People For COVID-19?

The CDC stated that Clinicians should use their judgment to determine if a patient has signs and symptoms compatible with COVID-19 and whether the patient should be tested. In addition, priority testing should be given to: Hospitalized patients who have signs and symptoms compatible with COVID-19 in order to inform decisions related to infection control. Other symptomatic individuals such as, older adults (ages 65 years or older) and individuals with chronic medical conditions and/or an immunocompromised state that may put them at higher risk for poor outcomes (e.g., diabetes, heart disease, receiving immunosuppressive medications, chronic lung disease, chronic kidney disease). Any persons including healthcare personnel, who within 14 days of symptom onset had close contact with a suspect or laboratory-confirmed COVID-19 patient, or who have a history of travel from affected geographic areas within 14 days of their symptom onset.  

COVID Antibody Test Limitations:

For use in clinical laboratories by health care professionals following FDA guidance Policy for Diagnostic Tests for Coronavirus Disease-2019 (COVID-19) during the Public Health Emergency. Negative results do not rule out SARS-CoV-2 infection, particularly in those who have been in contact with the virus. Follow-up testing with a molecular diagnostic assay (nasal swab) should be considered to rule out infection in these individuals. Results from antibody testing should not be used as the sole basis to diagnose or exclude SARS-CoV-2 infection or to inform infection status. Positive results may be due to past or present infection with non-SARS-CoV-2 coronavirus strains, such as coronavirus HKU1, NL63, OC43, or 229E. Not for the screening of donated blood.

Procedure

The COVID Antibody Test is a blood test that provides qualitative and quantitative detection of IgM and IgG antibodies against the SARS-CoV-2 in individuals suspected of COVID-19. After infection, the virus antigen stimulates the immune system to produce antibodies that can be detected in the blood. Among these antibodies, the IgM antibodies appear early and are mostly positive after 3-5 days of onset.

The IgM titers then decrease while the IgG antibody potency starts to rise rapidly. During the recovery phase, the titer of the IgG antibody may increase four times or more compared to the acute phase.

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* This is for educational purposes only. LabFinder does not provide medical advice, diagnosis or treatment. All users should consult with a medical provider in person for any health concerns.