Book HLA-B27 Test Near Me

What is an Human Leukocyte Antigen B27 Test?

The HLA-B27 Test, also known as Human Leukocyte Antigen B27 Test or HLA-B27 Antigen Test, is a blood test used to detect the presence of the HLA-B27 protein on the surface of white blood cells. This protein is associated with certain autoimmune and inflammatory conditions. The test helps healthcare providers identify if an individual has a genetic predisposition to conditions like ankylosing spondylitis, reactive arthritis, or other HLA-B27-related diseases. It is a valuable tool for diagnosing and managing autoimmune disorders.

Who Can Take the HLA-B27 Antigen Test?

The HLA-B27 Test, also referred to as the HLA-B27 Antigen Test, is recommended for individuals experiencing symptoms that may indicate an autoimmune or inflammatory condition. These symptoms include chronic back pain, stiffness, joint swelling, or unexplained inflammation in areas like the eyes or spine. It is commonly prescribed for individuals with a family history of HLA-B27-associated diseases or for those suspected of having conditions such as ankylosing spondylitis or reactive arthritis. The test is safe for most individuals and can be performed at any age.

When Can the HLA-B27 Test Be Performed?

The HLA-B27 Test can be performed whenever a healthcare provider suspects a patient may have an autoimmune condition linked to the HLA-B27 antigen. It is often ordered during the diagnostic process for unexplained chronic pain, inflammation, or recurring symptoms that do not have a clear cause. The test is particularly useful when other diagnostic tools, such as imaging or blood work, suggest the possibility of an HLA-B27-related disorder. It may also be performed as part of a comprehensive evaluation for patients with a family history of these conditions.

Procedure and Duration

The HLA-B27 Test is a simple blood test. During the procedure, a healthcare professional collects a small blood sample from a vein in the patient’s arm using a sterile needle. The blood sample is then sent to a laboratory for analysis to determine the presence of the HLA-B27 protein. The procedure typically takes about 5 to 10 minutes, including preparation and sample collection. Results are usually available within a few days, depending on the laboratory’s processing time. Patients can resume normal activities immediately after the test.

Related Conditions or Illnesses

The HLA-B27 Test is commonly associated with diagnosing and monitoring several autoimmune and inflammatory conditions. These include ankylosing spondylitis, a type of arthritis that primarily affects the spine, and reactive arthritis, which occurs in response to infections. The test is also used to evaluate conditions like uveitis, an inflammatory eye disorder, and psoriatic arthritis, a form of arthritis linked to psoriasis. Additionally, it helps diagnose inflammatory bowel diseases such as Crohn’s disease and ulcerative colitis when these conditions are suspected to have an HLA-B27 connection.

Risks

The HLA-B27 Test is a low-risk procedure. Some patients may experience mild discomfort, bruising, or swelling at the site where the blood sample is drawn, but these effects are temporary and resolve quickly. Rarely, individuals may feel lightheaded or faint during or after the blood draw. It is important to inform your healthcare provider if you have a history of fainting or difficulty with blood draws. Overall, the test is safe and well-tolerated by most patients.

Preparations

Preparing for an HLA-B27 Test is straightforward. Patients do not typically need to fast or make significant changes to their routine before the test. However, it is important to inform your healthcare provider about any medications, supplements, or underlying medical conditions that could affect your blood test results. Wearing comfortable clothing with easy access to your arm can make the process smoother. Following these simple preparations ensures a quick and efficient testing experience.

Other Similar Tests

Several other tests may complement or serve as alternatives to the HLA-B27 Test. A Complete Blood Count (CBC) is often performed alongside this test to evaluate overall health and detect signs of inflammation or infection. Erythrocyte Sedimentation Rate (ESR) and C-reactive Protein (CRP) tests are commonly used to assess inflammation levels in the body. Imaging studies, such as X-rays or MRI, may also be used to detect structural changes in joints or the spine associated with HLA-B27-related conditions. Each test provides unique insights and may be recommended based on the individual’s symptoms and medical history.

Book an HLA-B27 Test Using LabFinder

LabFinder makes it easy to book an HLA-B27 Test near your location. With our participating labs and imaging centers, you can schedule this test conveniently and find facilities that accept insurance. So, if you're looking for an "HLA-B27 Test near me," "HLA-B27 Antigen Test near me," or "Autoimmune Blood Test near me," you've come to the right place. LabFinder connects you with trusted labs, ensuring a seamless and efficient booking experience for your diagnostic needs.

Conclusion

The HLA-B27 Test is a vital diagnostic tool for identifying autoimmune and inflammatory conditions linked to the HLA-B27 antigen. By detecting the presence of this protein, the test helps healthcare providers diagnose, monitor, and manage conditions such as ankylosing spondylitis and reactive arthritis effectively. With LabFinder, you can easily book this test at a participating lab or imaging center near you, ensuring convenience and insurance compatibility. Take control of your health by scheduling your HLA-B27 Test with LabFinder today.


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Medically Reviewed by Dr. Robert Segal, MD, FACC

Reviewed by: Dr. Robert Segal, MD, FACC

Board-Certified Physician

Last Updated: December 20, 2025

The information on this page and throughout the LabFinder website and mobile app is for general informational purposes only. It is not intended to serve as medical advice, diagnosis, or treatment. For personalized medical advice or specific health concerns, please consult your healthcare provider directly.

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Frequently Asked Questions

  • Can I book a HLA-B27 Test near me?

    Booking a HLA-B27 Test is easy using LabFinder. Just choose your location and enter your insurance information to find the closest HLA-B27 Test near you.

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    To make a same-day appointment for a HLA-B27 Test, just choose your location and your insurance information to find the closest HLA-B27 Test location near you. If there's availability for a same-day appointment at a nearby lab location, then you will be able to book it easily through LabFinder.

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    LabFinder allows you to easily schedule a HLA-B27 Test. You can search by location and insurance to easily book a HLA-B27 Test near you.

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    LabFinder allows you to easily make an appointment for a HLA-B27 Test online. To make an appointment for a HLA-B27 Test online, just choose your location and your insurance information to find the closest HLA-B27 Test near you.

  • Can I get a HLA-B27 Test without insurance?

    Yes, you can get a HLA-B27 Test without insurance. LabFinder allows you to search and select "Self-Pay" when booking a HLA-B27 Test. While pricing for the test may not be immediately available, please check by calling the lab company directly for pricing.

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